Based on various health indicators, Lesotho is highly challenged by its terrain affecting its accessibility, health service delivery and lack of financial power. Despite enjoying series of investment in the health sectors and humanitarian activities, the country still remains the world third highest prevalence of HIV/AIDS at 23.4% in 2018 and it was considered a drawdown to the present life expectance of 54years. Family is known to form the basis for health development of a community and the nation as a whole. With family health consideration, the review examined how Lesotho can archive some of its Sustainable Development Goals (SDG) targets and explore the issue related to family health and its incorporation into the SDG.