Water purification remains a pressing concern globally, particularly in regions with limited access to clean water. Chemical coagulants, while effective, often pose environmental and health challenges. This review explores the viability of plant-based natural coagulants (PNCs) as sustainable, efficient, and eco-friendly alternatives for domestic and industrial water purification. Drawing from empirical research and case studies, we examine various plant sources, coagulation mechanisms, treatment efficiency, influencing factors, and scalability. The findings reveal that PNCs hold significant promise for enhancing water treatment, especially in resource-constrained communities.